Anti-Bov CD45R Purified
Product Sizes
0.1 mg
£181.00
11-352-0.1MG
About this Product
- SKU:
- 11-352
- Application:
- Flow Cytometry, Immunocytochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- IVA103
- Concentration:
- 1 mg/ml
- Extra Details:
- CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
- Immunogen:
- Bovine leukocytes.
- Isotype:
- IgG1
- Reactivities:
- Bovine
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody IVA103 reacts with an extracellular epitope of CD45R antigen (bovine), a single chain type I transmembrane glycoprotein (member of the protein tyrosine phosphatase family), a restricted form of the CD45 family. CD45R is an essential regulator of T and B lymphocytes antigen receptor signaling and it is specifically expressed in hematopoietic cells.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
