Anti-GAPDHS Purified
Product Sizes
0.025 mg
£127.00
11-301-0.025MG
0.1 mg
£213.00
11-301-0.1MG
About this Product
- SKU:
- 11-301
- Application:
- Flow Cytometry, Immunocytochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- Hs-8
- Concentration:
- 1 mg/ml
- Extra Details:
- GAPDHS (the sperm-specific glyceraldehyde phosphate dehydrogenase, also known as GAPD2, GAPDS, HSD-35, or GAPDH-2, is a glycolytic enzyme that plays an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. It can be used as an intra-acrosomal marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.
- Immunogen:
- Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
- Isotype:
- IgM
- Reactivities:
- Human, Porcine
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody Hs-8 reacts with GAPDHS, the sperm-specific glyceraldehyde phosphate dehydrogenase, which is an intra-acrosomal protein.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
