Anti-Hu CD279 Purified
Product Sizes
0.025 mg
£111.00
11-176-0.025MG
0.1 mg
£181.00
11-176-0.1MG
About this Product
- SKU:
- 11-176
- Application:
- Flow Cytometry, IHC-Frozen
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EH12.2H7
- Concentration:
- 1 mg/ml
- Extra Details:
- CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its ligands CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.
- Immunogen:
- recombinant human CD279
- Isotype:
- IgG1, kappa
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody EH12.2H7 recognizes an extracellular epitope of CD279 / PD-1 (programmed cell death 1), a 55 kDa type I transmembrane protein expressed above all during T cell development, on activated T cells, activated B cells, and activated monocytes.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
