Anti-Hu CD264 Purified Azide Free
Product Sizes
0.025 mg
£138.00
10-519-0.025MG
0.1 mg
£235.00
10-519-0.1MG
About this Product
- SKU:
- 10-519
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- TRAIL-R4-01
- Concentration:
- 1 mg/ml
- Extra Details:
- TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).
- Immunogen:
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
