Anti-Hu CD59 Purified Azide Free
Product Sizes
0.025 mg
£116.00
10-388-0.025MG
0.1 mg
£192.00
10-388-0.1MG
About this Product
- SKU:
- 10-388
- Application:
- Cell-based/Functional Assay, Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MEM-129
- Concentration:
- 1 mg/ml
- Extra Details:
- CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
- Immunogen:
- Human peripheral blood lymphocytes
- Isotype:
- IgM
- Reactivities:
- Human, Porcine
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody MEM-129 reacts with CD59 (Protectin), a 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored extracellular glycoprotein expressed on all hematopoietic cells; it is widely present on cells in all tissus.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
