Bovine Thrombin Protein
Product Sizes
2000U
£181.00
OPPA01776-2000U
About this Product
- SKU:
- OPPA01776
- Additional Names:
- Thrombin Bovine; Bovine Thrombin
- Extra Details:
- Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein and a serine protease (EC 3.4.21.5) that catalyzes many coagulation-related reactions. Thrombin triggers factor-XI; factor-V; Factor-XIII and factor-VIII. Thrombin endorses platelet activation; using activation of protease-activated receptors on the platelet. As a result of its high proteolytic specificity; thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein; thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site; efficiently removing the purification tag from the protein of interest with a high degree of specificity.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- It is recommended to reconstitute the lyophilized Thrombin in in 0.9% NaCl. Lyophilized Thrombin; although stable at room temperature for 3 weeks; should be stored desiccated below -18°C. Upon reconstitution Thrombin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:html_datasheet.php
