BIRC7 Protein
Product Sizes
5µg
£186.00
OPPA01727-5UG
20µg
£294.00
OPPA01727-20UG
About this Product
- SKU:
- OPPA01727
- Additional Names:
- KIAP; LIVIN; MLIAP; RNF50; ML-IAP
- Concentration:
- 1 mg/ml
- Extra Details:
- BIRC7 is a part of the inhibitor of apoptosis protein (IAP) family and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is necessary for inhibitory activity & cooperates with caspases; while the RING finger domain sometimes increases anti-apoptotic activity but doesn't inhibit apoptosis by itself. 2 transcript variants encoding diverse isoforms have been found for this gene. The 2 isoforms have dissimilar antiapoptotic characteristics; with isoform a protecting cells from apoptosis induced by staurosporine and isoform b defending cells from apoptosis. BIRC7 has direct contact with several caspases together with caspase-3; caspase-7; & caspase –9. BIRC7 inhibits the activation of caspase-9 induced by Apaf-1; cytochrome c; and dATP.
- Molecular Weight:
- 34 kDa
- Protein Details:
- Baculoviral IAP repeat-containing protein 7
- Purity:
- Greater than 90.0% as determined by SDS-PAGE.
- Purification:
- Purified by proprietary chromatographic techniques.
- Shipping Conditions:
- Blue Ice
- Source:
- E. Coli
- Storage Conditions:
- Store at 4C if entire vial will be used within 2-4 weeks. Store; frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:html_datasheet.php
