Bax Protein
Product Sizes
2µg
£186.00
OPPA01324-2UG
About this Product
- SKU:
- OPPA01324
- Additional Names:
- Apoptosis regulator BAX membrane isoform alpha; Bax; Bcl2-associated X protein; Bax Mouse; Bax Mouse Recombinant
- Extra Details:
- Bcl-2 - associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1; BH2 and BH3 domains. Bax accelerates programmed cell death by binding to; and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c; activation of casp3; and thereby apoptosis. Bax is expressed in a wide variety of tissues; with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
- Host:
- E. coli
- Protein Details:
- Apoptosis regulator BAX
- Purity:
- Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Purification:
- The Mouse Bax is purified by proprietary chromatographic techniques.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Mouse Bax although stable at 12C for 1 week; should be stored desiccated below -18C. Please prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:html_datasheet.php
