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S100A1 Protein

Product Sizes
5µg
£366.00
OPPA01277-5UG
About this Product
SKU:
OPPA01277
Additional Names:
S100; S100A; S100-alpha
Extra Details:
S100A1 is a member of the S100 family of calcium binding proteins with EF-hand type Ca+2 binding motive. S100A1 (Calcium Binding Protein A1) is involved in the activation of sarcoplasmatic calcium release and the regulation of intermediate filament polymerization. S100A1 may function in stimulation of Ca2+-induced Ca2+ release; inhibition of microtubule assembly; and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of S100A1 has been implicated in cardiomyopathies.
S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family; which are located as a cluster on chromosome 1q21.
Protein Details:
Protein S100-A1
Purity:
Greater than 95.0% as determined by SDS-PAGE.
Purification:
S100A1 Human Recombinant is purified by proprietary chromatographic techniques.
Shipping Conditions:
Ambient
Source:
E. coli
Storage Conditions:
Reconstitution: Add deionized water to a working concentration approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture.
Storage: Lyophilized S100A1 although stable at room temperature for 3 weeks; should be stored desiccated below -18C. Upon reconstitution S100A1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules