TRAIL Protein
Product Sizes
10µg
£186.00
OPPA00702-10UG
About this Product
- SKU:
- OPPA00702
- Additional Names:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- Extra Details:
- TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans; the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors; DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
- Molecular Weight:
- ~21 kDa
- Protein Details:
- Tumor necrosis factor ligand superfamily member 10
- Purity:
- Greater than 95.0% as determined by:<br> (a) Analysis by RP-HPLC<br>(b) Analysis by SDS-PAGE
- Purification:
- The sTRAIL is purified by proprietary chromatographic techniques.
- Shipping Conditions:
- Ambient
- Source:
- E. Coli
- Storage Conditions:
- It is recommended to reconstitute the lyophilized TRAIL in sterile 18MΩ-cm H2O not less than 100μg/ml; which can then be further diluted to other aqueous solutions.
Lyophilized APO 2 Ligand although stable at room temperature for 3 weeks; should be stored desiccated below -18Â[o]C. Upon reconstitution TRAIL should be stored at 4°Cbetween 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. - Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:html_datasheet.php
