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Proteins and Peptides

FASLG Recombinant Protein

Product Sizes
10 ug
£485.00
OPED00043-10UG
About this Product
SKU:
OPED00043
Additional Names:
ALPS1B;apoptosis (APO-1) antigen ligand 1;apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95 ligand;CD95L;CD95-L;fas antigen ligand;Fas ligand (TNF superfamily; member 6);FASL;mutant tumor necrosis factor family member 6;TNFSF6;TNLG1A;tumor necrosis factor ligand 1A;tumor necrosis factor ligand superfamily member 6.
Extra Details:
Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:26334989; PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058; PubMed:7528780; PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (PubMed:27806260).
Gene Details:
Fas ligand
Molecular Weight:
32 kDa; 35 kDa (glycosylated)
Protein Details:
Tumor necrosis factor ligand superfamily member 6
Purity:
>95% (SDS-PAGE)
Purification:
Purified by multi-step chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Reconstitute with 100 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. Store at -20C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins