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Proteins and Peptides

FAS Recombinant Protein

Product Sizes
50 ug
£691.00
OPED00042-50UG
About this Product
SKU:
OPED00042
Additional Names:
ALPS1A;APO-1;Apo-1 antigen;APO-1 cell surface antigen;apoptosis antigen 1;apoptosis signaling receptor FAS;apoptosis-mediating surface antigen FAS;APT1;CD95;CD95 antigen;Fas (TNF receptor superfamily; member 6);Fas AMA;FAS1;FASLG receptor;FASTM;mutant tumor necrosis receptor superfamily member 6;TNF receptor superfamily member 6;TNFRSF6;tumor necrosis factor receptor superfamily member 6;tumor necrosis factor receptor superfamily; member 6.
Extra Details:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance; in the antigen-stimulated suicide of mature T-cells; or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Gene Details:
Fas cell surface death receptor
Molecular Weight:
56 kDa
Protein Details:
Tumor necrosis factor receptor superfamily member 6
Purity:
>95% (SDS-PAGE)
Purification:
Purified by multi-step chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Reconstitute with 50 ul sterile water. Further dilutions can be made with medium containing 5% fetal calf serum or a carrier protein. Store at -20C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins