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Proteins and Peptides

TRADD Recombinant Protein

Product Sizes
10ug
£257.00
OPCD07694-10UG
50ug
£496.00
OPCD07694-50UG
200ug
£886.00
OPCD07694-200UG
About this Product
SKU:
OPCD07694
Additional Names:
Hs.89862;TNFR1-associated death domain protein;TNFRSF1A-associated via death domain;tumor necrosis factor receptor type 1 associated death domain protein;tumor necrosis factor receptor type 1-associated DEATH domain protein;tumor necrosis factor receptor-1-associated protein.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12; leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses; apoptosis and activation of NF-kappa-B.
Gene Details:
TNFRSF1A associated via death domain
Host:
E. coli
Molecular Weight:
32kDa
Protein Details:
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Purity:
> 97%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins