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Proteins and Peptides

TLR1 Recombinant Protein

Product Sizes
10ug
£218.00
OPCD07486-10UG
50ug
£387.00
OPCD07486-50UG
200ug
£673.00
OPCD07486-200UG
About this Product
SKU:
OPCD07486
Additional Names:
CD281;rsc786;TIL;TIL. LPRS5;toll/interleukin-1 receptor-like protein;toll-like receptor 1.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides; this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response.
Gene Details:
toll like receptor 1
Host:
E. coli
Molecular Weight:
28kDa
Protein Details:
Toll-like receptor 1
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins