TICAM1 Recombinant Protein
Product Sizes
10ug
£283.00
OPCD07436-10UG
50ug
£554.00
OPCD07436-50UG
200ug
£1009.00
OPCD07436-200UG
About this Product
- SKU:
- OPCD07436
- Additional Names:
- AW046014;AW547018;TICAM;TICAM-1;TIR domain-containing adapter molecule 1;TIR domain-containing adapter protein inducing IFN-beta;TIR domain-containing adaptor inducing interferon-beta;toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;Tr;TRIF.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation; and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1; TRAF6 and RIPK1; which in turn; lead to the activation of transcription factors IRF3 and IRF7; NF-kappa-B and FADD respectively.
- Gene Details:
- toll-like receptor adaptor molecule 1
- Host:
- E. coli
- Molecular Weight:
- 39kDa
- Protein Details:
- TIR domain-containing adapter molecule 1
- Purity:
- > 97%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
