SP100 Recombinant Protein
Product Sizes
10ug
£257.00
OPCD07124-10UG
50ug
£489.00
OPCD07124-50UG
200ug
£879.00
OPCD07124-200UG
About this Product
- SKU:
- OPCD07124
- Additional Names:
- lysp100b;nuclear autoantigen Sp-100;nuclear dot-associated Sp100 protein;SP100-HMG nuclear autoantigen;speckled 100 kDa.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Together with PML; this tumor suppressor is a major constituent of the PML bodies; a subnuclear organelle involved in a large number of physiological processes including cell growth; differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2 according to PubMed:11909962. Under certain conditions; it may also act as a corepressor of ETS1 preventing its binding to DNA according to PubMed:15247905. Through the regulation of ETS1 it may play a role in angiogenesis; controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2; regulate FAS-mediated apoptosis. Also plays a role in infection by viruses; including human cytomegalovirus and Epstein-Barr virus; through mechanisms that may involve chromatin and/or transcriptional regulation.
- Gene Details:
- SP100 nuclear antigen
- Host:
- E. coli
- Molecular Weight:
- 31kDa
- Protein Details:
- Nuclear autoantigen Sp-100
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
