SLC3A2 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD07035-10UG
50ug
£539.00
OPCD07035-50UG
200ug
£977.00
OPCD07035-200UG
About this Product
- SKU:
- OPCD07035
- Additional Names:
- 4F2 cell-surface antigen heavy chain;4F2hc;antigen identified by monoclonal antibodies 4F2;Mdu1;solute carrier family 3 (activators of dibasic and neutral amino acid transport); member 2;solute carrier family 3 (amino acid transporter heavy chain); member 2;Solute carrier family 3 member 2.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Required for the function of light chain amino-acid transporters. Involved in sodium-independent; high-affinity transport of large neutral amino acids such as phenylalanine; tyrosine; leucine; arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger; following an antiport mechanism for amino acid transport; influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1; is also involved in the transport of L-DOPA across the blood-brain barrier; and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D;L-homocysteine complexes; and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8; involved in the cellular activity of small molecular weight nitrosothiols; via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1; regulates the transport activity LAT2 in polarized intestinal cells; by generating and delivering intracellular signals. When associated with SLC7A5; plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier. When associated with LAPTM4B; recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (By similarity).
- Gene Details:
- solute carrier family 3 member 2
- Host:
- E. coli
- Molecular Weight:
- 56kDa
- Protein Details:
- 4F2 cell-surface antigen heavy chain
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
