SIRPA Recombinant Protein
Product Sizes
10ug
£268.00
OPCD06990-10UG
50ug
£522.00
OPCD06990-50UG
200ug
£940.00
OPCD06990-200UG
About this Product
- SKU:
- OPCD06990
- Additional Names:
- Bit;brain Ig-like molecule with tyrosine-based activation motifs;Brain immunoglobulin like protein with tyrosine - based activation motifs;CD172 antigen-like family member A;inhibitory receptor SHPS-1;macrophage fusion receptor;macrophage membrane protein MFP150;Protein tyrosine phosphatase; non-receptor type substrate 1 (SHP substrate 1);Ptpns1;SHP substrate 1;SHPS-1;signal-regulatory protein alpha-1;sirp-alpha-1;tyrosine-protein phosphatase non-receptor type substrate 1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6; PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons; neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion; growth factors or insulin. Mediates negative regulation of phagocytosis; mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. May play a role in the release of nitric oxide by macrophages (By similarity).
- Gene Details:
- signal-regulatory protein alpha
- Host:
- E. coli
- Molecular Weight:
- 27kDa
- Protein Details:
- Tyrosine-protein phosphatase non-receptor type substrate 1
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
