RUNX2 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD06761-10UG
50ug
£543.00
OPCD06761-50UG
200ug
£988.00
OPCD06761-200UG
About this Product
- SKU:
- OPCD06761
- Additional Names:
- acute myeloid leukemia 3 protein;AML3;CBFA1;CBF-alpha-1;CCD;CCD1;CLCD;Core-binding factor subunit alpha-1;core-binding factor; runt domain; alpha subunit 1;oncogene AML-3;OSF2;OSF-2;osteoblast-specific transcription factor 2;PEA2aA;PEA2-alpha A;PEBP2aA;PEBP2-alpha A;polyomavirus enhancer-binding protein 2 alpha A subunit;runt related transcription factor 2;runt-related transcription factor 2;SL3/AKV core-binding factor alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335; PubMed:28738062; PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; osteocalcin; osteopontin; bone sialoprotein; alpha 1(I) collagen; LCK; IL-3 and GM-CSF promoters. In osteoblasts; supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
- Gene Details:
- RUNX family transcription factor 2
- Host:
- E. coli
- Molecular Weight:
- 26kDa
- Protein Details:
- Runt-related transcription factor 2
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
