PVR Recombinant Protein
Product Sizes
10ug
£272.00
OPCD06538-10UG
50ug
£528.00
OPCD06538-50UG
200ug
£955.00
OPCD06538-200UG
About this Product
- SKU:
- OPCD06538
- Additional Names:
- CD155;HVED;Necl-5;NECL5;nectin-like protein 5;poliovirus receptor;PVS;TAGE4.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site; leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange; and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR; and may trigger fratricide NK cell activation; providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.
- Gene Details:
- PVR cell adhesion molecule
- Host:
- E. coli
- Molecular Weight:
- 32kDa
- Protein Details:
- Poliovirus receptor
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
