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Proteins and Peptides

PTGS2 Recombinant Protein

Product Sizes
10ug
£240.00
OPCD06484-10UG
50ug
£446.00
OPCD06484-50UG
200ug
£788.00
OPCD06484-200UG
About this Product
SKU:
OPCD06484
Additional Names:
COX2;COX-2;cyclooxygenase 2;cyclooxygenase 2b;Cyclooxygenase-2;GRIPGHS;hCox-2;PGG/HS;PGH synthase 2;PGHS-2;PHS II;PHS-2;prostaglandin G/H synthase 2;prostaglandin H2 synthase 2;Prostaglandin-endoperoxide synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase).
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Converts arachidonate to prostaglandin H2 (PGH2); a committed step in prostanoid synthesis (PubMed:26859324; PubMed:27226593). Constitutively expressed in some tissues in physiological conditions; such as the endothelium; kidney and brain; and in pathological conditions; such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion; phenotypic changes; resistance to apoptosis and tumor angiogenesis. In cancer cells; PTGS2 is a key step in the production of prostaglandin E2 (PGE2); which plays important roles in modulating motility; proliferation and resistance to apoptosis.
Gene Details:
prostaglandin-endoperoxide synthase 2
Host:
E. coli
Molecular Weight:
25kDa
Protein Details:
Prostaglandin G/H synthase 2
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins