PPIF Recombinant Protein
Product Sizes
10ug
£272.00
OPCD06348-10UG
50ug
£528.00
OPCD06348-50UG
200ug
£955.00
OPCD06348-200UG
About this Product
- SKU:
- OPCD06348
- Additional Names:
- AW457192;cyclophilin D;cyclophilin F;Cyp;CyP-;CypD;CyP-D;CyP-F;mitochondrial Cyclophilin D;peptidyl-prolyl cis-trans isomerase F; mitochondrial;peptidyl-prolyl cis-trans isomerase; mitochondrial;PPIase;PPIase F;rotamase F.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
- Gene Details:
- peptidylprolyl isomerase F (cyclophilin F)
- Host:
- E. coli
- Molecular Weight:
- 22kDa
- Protein Details:
- Peptidyl-prolyl cis-trans isomerase F; mitochondrial
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
