CD274 Recombinant Protein
Product Sizes
10ug
£261.00
OPCD06040-10UG
50ug
£500.00
OPCD06040-50UG
200ug
£901.00
OPCD06040-200UG
About this Product
- SKU:
- OPCD06040
- Additional Names:
- B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;programmed cell death 1 ligand 1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279; modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417; PubMed:28813410). Through a yet unknown activating receptor; may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
- Gene Details:
- CD274 molecule
- Host:
- E. coli
- Molecular Weight:
- 32kDa
- Protein Details:
- Programmed cell death 1 ligand 1
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
