BMI1 Recombinant Protein
Product Sizes
10ug
£225.00
OPCD06009-10UG
50ug
£409.00
OPCD06009-50UG
200ug
£712.00
OPCD06009-200UG
About this Product
- SKU:
- OPCD06009
- Additional Names:
- B lymphoma Mo-MLV insertion region 1 homolog;BMI1;BMI1 polycomb ring finger oncogene;BMI1 polycomb ring finger proto-oncogene;COMMD3-BMI1 read-through protein;flvi-2/bmi-1;FLVI2/BMI1;murine leukemia viral (bmi-1) oncogene homolog;PCGF4;polycomb complex protein BMI-1;polycomb group protein Bmi1;polycomb group RING finger protein 4;ring finger protein 51;RNF51.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Component of a Polycomb group (PcG) multiprotein PRC1-like complex; a complex class required to maintain the transcriptionally repressive state of many genes; including Hox genes; throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119'; rendering chromatin heritably changed in its expressibility (PubMed:15386022; PubMed:16359901; PubMed:26151332; PubMed:16714294; PubMed:21772249; PubMed:25355358; PubMed:27827373). The complex composed of RNF2; UB2D3 and BMI1 binds nucleosomes; and has activity only with nucleosomal histone H2A (PubMed:21772249; PubMed:25355358). In the PRC1-like complex; regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022; PubMed:26151332; PubMed:21772249).
- Gene Details:
- BMI1 proto-oncogene; polycomb ring finger|COMMD3-BMI1 readthrough
- Host:
- E. coli
- Molecular Weight:
- 24kDa
- Protein Details:
- Polycomb complex protein BMI-1
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
