NME1 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD05683-10UG
50ug
£550.00
OPCD05683-50UG
200ug
£998.00
OPCD05683-200UG
About this Product
- SKU:
- OPCD05683
- Additional Names:
- AL024257;expressed in non-metastatic cells 1; protein;metastasis inhibition factor NM23;NDK A;NDP;NDP kinase A;NDPK-A;NM23A;NM23-M;NM23-M1;non-metastatic cells 1; protein (NM23A) expressed in;nucleoside diphosphate kinase A;nucleoside-diphosphate kinase 1;nucleotide diphosphate kinase;tumor metastatic process-associated protein.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism; using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase; serine/threonine-specific protein kinase; geranyl and farnesyl pyrophosphate kinase; histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation; differentiation and development; signal transduction; G protein-coupled receptor endocytosis; and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death; works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair (By similarity).
- Gene Details:
- NME/NM23 nucleoside diphosphate kinase 1
- Host:
- E. coli
- Molecular Weight:
- 20kDa
- Protein Details:
- Nucleoside diphosphate kinase A
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
