CD177 Recombinant Protein
Product Sizes
10ug
£272.00
OPCD05582-10UG
50ug
£528.00
OPCD05582-50UG
200ug
£955.00
OPCD05582-200UG
About this Product
- SKU:
- OPCD05582
- Additional Names:
- 1190003K14Rik;CD177 antigen;Pd;Pdp3.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18; mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition; by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However; appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:25359465). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (By similarity). By displaying PRTN3 at the neutrophil cell surface; may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (By similarity).
- Gene Details:
- CD177 antigen
- Host:
- E. coli
- Molecular Weight:
- 34kDa
- Protein Details:
- CD177 antigen
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
