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Proteins and Peptides

MAPRE1 Recombinant Protein

Product Sizes
10ug
£268.00
OPCD05134-10UG
50ug
£511.00
OPCD05134-50UG
200ug
£918.00
OPCD05134-200UG
About this Product
SKU:
OPCD05134
Additional Names:
adenomatous polyposis coli-binding protein EB1;APC-binding protein EB1;EB1;end-binding protein 1;microtubule-associated protein RP/EB family member 1.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). Promotes cytoplasmic microtubule nucleation and elongation (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (PubMed:12388762). Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP; leading to recruit CAMSAP2 to the Golgi apparatus; thereby tethering non-centrosomal minus-end microtubules to the Golgi; an important step for polarized cell movement (PubMed:28814570). Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570). Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (PubMed:28726242). May play a role in cell migration (By similarity).
Gene Details:
microtubule associated protein RP/EB family member 1
Host:
E. coli
Molecular Weight:
33.56kDa
Protein Details:
Microtubule-associated protein RP/EB family member 1
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins