MAPK7 Recombinant Protein
Product Sizes
10ug
£261.00
OPCD05124-10UG
50ug
£500.00
OPCD05124-50UG
200ug
£901.00
OPCD05124-200UG
About this Product
- SKU:
- OPCD05124
- Additional Names:
- b2b2346C;b2b2346Clo;big MAP kinase 1;BMK1;BMK-1;ERK;ERK5;Erk5-;ERK-5;Erk5-T;extracellular signal-regulated kinase 5;MAPK 7;mitogen-activated protein kinase 7;PRKM7.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Plays a role in various cellular processes such as proliferation; differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation; it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (By similarity). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction (By similarity).
- Gene Details:
- mitogen-activated protein kinase 7
- Host:
- E. coli
- Molecular Weight:
- 30&24kDa
- Protein Details:
- Mitogen-activated protein kinase 7
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
