LRP6 Recombinant Protein
Product Sizes
10ug
£268.00
OPCD05031-10UG
50ug
£517.00
OPCD05031-50UG
200ug
£933.00
OPCD05031-200UG
About this Product
- SKU:
- OPCD05031
- Additional Names:
- ADCAD2;low-density lipoprotein receptor-related protein 6;LRP-6;STHAG7.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling; which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which; in turn; recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
- Gene Details:
- LDL receptor related protein 6
- Host:
- E. coli
- Molecular Weight:
- 30kDa
- Protein Details:
- Low-density lipoprotein receptor-related protein 6
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
