PSMB8 Recombinant Protein
Product Sizes
10ug
£272.00
OPCD04978-10UG
50ug
£532.00
OPCD04978-50UG
200ug
£962.00
OPCD04978-200UG
About this Product
- SKU:
- OPCD04978
- Additional Names:
- ALDD;D6S216;D6S216E;JMP;LMP7;low molecular mass protein 7;low molecular weight protein 7;macropain subunit C13;multicatalytic endopeptidase complex subunit C13;NKJO;PRAAS1;protease component C13;proteasome (prosome; macropain) subunit; beta type; 8 (large multifunctional peptidase 7);proteasome catalytic subunit 3i;proteasome component C13;proteasome subunit beta 5i;proteasome subunit beta 8;proteasome subunit beta type-8;Proteasome subunit beta-5i;proteasome subunit Y2;proteasome-related gene 7;PSMB5i;really interesting new gene 10 protein;RING10.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg; Phe; Tyr; Leu; and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells; substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.
- Gene Details:
- proteasome 20S subunit beta 8
- Host:
- E. coli
- Molecular Weight:
- 24kDa
- Protein Details:
- Proteasome subunit beta type-8
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
