MKI67 Recombinant Protein
Product Sizes
10ug
£268.00
OPCD04655-10UG
50ug
£511.00
OPCD04655-50UG
200ug
£918.00
OPCD04655-200UG
About this Product
- SKU:
- OPCD04655
- Additional Names:
- antigen identified by monoclonal antibody Ki-67 homolog;antigen Ki67 homolog;antigen KI-67 homolog;D630048A14Rik;Ki6;Ki-6;Ki67;Ki-67;proliferation marker protein Ki-67.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome; the perichromosomal layer; and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant; dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA; with a preference for supercoiled DNA and AT-rich DNA (By similarity). Does not contribute to the internal structure of mitotic chromosomes (PubMed:26949251). May play a role in chromatin organization (PubMed:26949251). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
- Gene Details:
- antigen identified by monoclonal antibody Ki 67
- Host:
- E. coli
- Molecular Weight:
- 19/44kDa
- Protein Details:
- Proliferation marker protein Ki-67
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
