ITGB2 Recombinant Protein
Product Sizes
10ug
£261.00
OPCD04593-10UG
50ug
£500.00
OPCD04593-50UG
200ug
£901.00
OPCD04593-200UG
About this Product
- SKU:
- OPCD04593
- Additional Names:
- CD18;cell surface adhesion glycoprotein (LFA-1/CR3/P150;959 beta subunit precursor);Cell surface adhesion glycoproteins LFA-1/CR3/p150;95 subunit beta;complement component 3 receptor 3 and 4 subunit;complement receptor C3 beta-subunit;Complement receptor C3 subunit beta;integrin beta chain; beta 2;integrin beta-2;integrin; beta 2 (complement component 3 receptor 3 and 4 subunit);LAD;LCAMB;leukocyte cell adhesion molecule CD18;leukocyte-associated antigens CD18/11A; CD18/11B; CD18/11C;LFA-1;MAC-1;MF17;MFI7;truncated integrin beta-2.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Integrin ITGAL/ITGB2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992; PubMed:28807980). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin ITGAL/ITGB2 in association with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). In association with alpha subunit ITGAM/CD11b; required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407).
- Gene Details:
- integrin subunit beta 2
- Host:
- E. coli
- Molecular Weight:
- 56kDa
- Protein Details:
- Integrin beta-2
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
