ILF3 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD04467-10UG
50ug
£543.00
OPCD04467-50UG
200ug
£994.00
OPCD04467-200UG
About this Product
- SKU:
- OPCD04467
- Additional Names:
- CBTF;Double-stranded RNA-binding protein 76;double-stranded RNA-binding protein; 76 kD;DRBF;DRBP76;dsRNA binding protein NFAR-2/MPP4;interleukin enhancer binding factor 3; 90kD;interleukin enhancer binding factor 3; 90kDa;interleukin enhancer-binding factor 3;M phase phosphoprotein 4; nuclear factor associated with DS RNA;MMP4;M-phase phosphoprotein 4;MPHOSPH4;MPP4;MPP4110;NF110;NF110b;NF90;NF90a;NF90b;NF90c;NF90ctv;NFAR;NFAR-1;NFAR110;NFAR2;NFAR-2;NFAR90;NF-AT-90;nuclear factor associated with dsRNA;nuclear factor of activated T-cells 110 kDa;nuclear factor of activated T-cells 90 kDa;nuclear factor of activated T-cells; 90 kD;TCP110;TCP80;translational control protein 80.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus; promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs (PubMed:28625552). As a consequence; participates in a wide range of transcriptional and post-transcriptional processes. Upon viral infection; ILF3 accumulates in the cytoplasm and participates in the innate antiviral response (PubMed:21123651). Mechanistically; ILF3 becomes phosphorylated and activated by the double-stranded RNA-activated protein kinase/PKR which releases ILF3 from cellular mature circRNAs. In turn; unbound ILF3 molecules are able to interact with and thus inhibit viral mRNAs (PubMed:21123651; PubMed:28625552).
- Gene Details:
- interleukin enhancer binding factor 3
- Host:
- E. coli
- Molecular Weight:
- 29kDa
- Protein Details:
- Interleukin enhancer-binding factor 3
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
