IFNAR1 Recombinant Protein
Product Sizes
10ug
£305.00
OPCD04119-10UG
50ug
£604.00
OPCD04119-50UG
200ug
£1107.00
OPCD04119-200UG
About this Product
- SKU:
- OPCD04119
- Additional Names:
- I;If;Ifar;IFN-alpha/beta receptor 1;IFN-alpha/betaR;Ifnar;IFN-R-1;Ifrc;INF-a receptor;Infar;interferon alpha/beta receptor 1;type I interferon receptor 1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Component of the receptor for type I interferons; including interferons alpha; IFNB1 and IFNW1 (PubMed:1533935; PubMed:14532120; PubMed:23872679). Functions in general as heterodimer with IFNAR2 (By similarity). Type I interferon binding activates the JAK-STAT signaling cascade; and triggers tyrosine phosphorylation of a number of proteins including JAKs; TYK2; STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:14532120). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (PubMed:23872679). Contributes to modulate the innate immune response to bacterial lipopolysaccharide (PubMed:23872679).
- Gene Details:
- interferon (alpha and beta) receptor 1
- Host:
- E. coli
- Molecular Weight:
- 28kDa
- Protein Details:
- Interferon alpha/beta receptor 1
- Purity:
- > 97%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
