HSPA5 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD04021-10UG
50ug
£539.00
OPCD04021-50UG
200ug
£977.00
OPCD04021-200UG
About this Product
- SKU:
- OPCD04021
- Additional Names:
- 78 kDa glucose-regulated protein;78kD;AL022860;AU019543;B;baffl;baffled;binding-immunoglobulin protein;Bip;D2Wsu141;D2Wsu141e;D2Wsu17;D2Wsu17e;endoplasmic reticulum chaperone BiP;glucose regulated protein; 78 kDa;Grp;Grp78;GRP-78;heat shock 70 kDa protein 5;heat shock 70kD protein 5 (glucose-regulated protein; 78kD);heat shock protein 70 family protein 5;heat shock protein family A member 5;Hsce7;Hsce70;HSP70 family protein 5;immunoglobulin heavy chain-binding protein;mB;mBiP;Sez;Sez7;SEZ-7;XAP-1 antigen.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (PubMed:12411443; PubMed:12475965). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5; probably to facilitate the release of DNAJC10/ERdj5 from its substrate (PubMed:12411443). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). In the unstressed endoplasmic reticulum; recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1; leading to disrupt the dimerization of ERN1/IRE1; thereby inactivating ERN1/IRE1 (By similarity). Accumulation of misfolded protein in the endoplasmic reticulum causes release of HSPA5/BiP from ERN1/IRE1; allowing homodimerization and subsequent activation of ERN1/IRE1 (By similarity).
- Gene Details:
- heat shock protein 5
- Host:
- E. coli
- Molecular Weight:
- 25kDa
- Protein Details:
- Endoplasmic reticulum chaperone BiP
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
