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Proteins and Peptides

GSAP Recombinant Protein

Product Sizes
10ug
£261.00
OPCD03710-10UG
50ug
£506.00
OPCD03710-50UG
200ug
£912.00
OPCD03710-200UG
About this Product
SKU:
OPCD03710
Additional Names:
gamma-secretase-activating protein;pigeon homolog;PION;protein pigeon homolog.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Regulator of gamma-secretase activity; which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42); without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta; while it reduces the epsilon-cleavage of APP CTF-alpha; leading to a low production of AICD.
Gene Details:
gamma-secretase activating protein
Host:
E. coli
Molecular Weight:
32kDa
Protein Details:
Gamma-secretase-activating protein
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins