GDF15 Recombinant Protein
Product Sizes
10ug
£290.00
OPCD03489-10UG
50ug
£565.00
OPCD03489-50UG
200ug
£1031.00
OPCD03489-200UG
About this Product
- SKU:
- OPCD03489
- Additional Names:
- GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099; PubMed:23468844; PubMed:29046435). Binds to its receptor; GFRAL; and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala; which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes; inhibits growth hormone signaling (By similarity).
- Gene Details:
- growth differentiation factor 15
- Host:
- E. coli
- Molecular Weight:
- 16kDa
- Protein Details:
- Growth/differentiation factor 15
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
