EGR1 Recombinant Protein
Product Sizes
10ug
£290.00
OPCD02875-10UG
50ug
£576.00
OPCD02875-50UG
200ug
£1048.00
OPCD02875-200UG
About this Product
- SKU:
- OPCD02875
- Additional Names:
- A530045N19Rik;early growth response protein 1;egr;Egr-;Egr-1;ETR10;ETR103;Krox;Krox-;Krox-1;Krox24;Krox-24;Krox-24 nuclear protein;nerve growth factor-induced protein A;NG;NGF;NGF1;NGF1-A;NGFIA;NGFI-A;TI;TIS8;transcription factor Zif268;Zen;Zenk;Zfp-;Zfp-6;Zif26;Zif268;zinc finger protein Krox-24.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Transcriptional regulator (PubMed:8336701; PubMed:8703054; PubMed:15958557). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (PubMed:8703054; PubMed:15958557; PubMed:2028256; PubMed:8939742). Binds double-stranded target DNA; irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes; and thereby plays an important role in regulating the response to growth factors; DNA damage; and ischemia (PubMed:11100120; PubMed:15958557). Plays a role in the regulation of cell survival; proliferation and cell death (PubMed:15265859; PubMed:15958557). Activates expression of p53/TP53 and TGFB1; and thereby helps prevent tumor formation (PubMed:15958557). Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy (PubMed:15265859). Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia (PubMed:11100120). Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (PubMed:8703054).
- Gene Details:
- early growth response 1
- Host:
- E. coli
- Molecular Weight:
- 22/27kDa
- Protein Details:
- Early growth response protein 1
- Purity:
- > 97%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
