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Proteins and Peptides

DPP4 Recombinant Protein

Product Sizes
10ug
£268.00
OPCD02789-10UG
50ug
£517.00
OPCD02789-50UG
200ug
£933.00
OPCD02789-200UG
About this Product
SKU:
OPCD02789
Additional Names:
bile canaliculus domain-specific membrane glycoprotein;CD26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;DPP IV;DPPIV;GP110 glycoprotein;T-cell activation antigen CD26.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation; by binding at least ADA; CAV1; IGF2R; and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM); the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion; migration and tube formation. When overexpressed; enhanced cell proliferation; a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation; including many chemokines; mitogenic growth factors; neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Gene Details:
dipeptidylpeptidase 4
Host:
E. coli
Molecular Weight:
15kDa
Protein Details:
Dipeptidyl peptidase 4
Purity:
> 90%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins