DKK3 Recombinant Protein
Product Sizes
10ug
£235.00
OPCD02748-10UG
50ug
£435.00
OPCD02748-50UG
200ug
£766.00
OPCD02748-200UG
About this Product
- SKU:
- OPCD02748
- Additional Names:
- dickkopf 3 homolog;dickkopf homolog 3;dickkopf-3;dickkopf-related protein 3;dkk-3;hDkk-3;regulated in glioma;REIC;RIG;RIG-like 5-6;RIG-like 7-1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease (By similarity).
- Gene Details:
- dickkopf WNT signaling pathway inhibitor 3
- Molecular Weight:
- 46kDa
- Protein Details:
- Dickkopf-related protein 3
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
