PPID Recombinant Protein
Product Sizes
10ug
£268.00
OPCD02637-10UG
50ug
£522.00
OPCD02637-50UG
200ug
£940.00
OPCD02637-200UG
About this Product
- SKU:
- OPCD02637
- Additional Names:
- 40 kDa peptidyl-prolyl cis-trans isomerase;40 kDa peptidyl-prolyl cis-trans isomerase D;cyclophilin 40;cyclophilin D;Cyclophilin-40;cyclophilin-related protein;CYP-40;CYPD;peptidyl-prolyl cis-trans isomerase D;PPIase D;rotamase D;testicular tissue protein Li 147.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:11350175; PubMed:20676357). Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines.
- Gene Details:
- peptidylprolyl isomerase D
- Host:
- E. coli
- Molecular Weight:
- 28kDa
- Protein Details:
- Peptidyl-prolyl cis-trans isomerase D
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
