CXADR Recombinant Protein
Product Sizes
10ug
£279.00
OPCD02581-10UG
50ug
£539.00
OPCD02581-50UG
200ug
£977.00
OPCD02581-200UG
About this Product
- SKU:
- OPCD02581
- Additional Names:
- 46 kD coxsackievirus and adenovirus receptor (CAR) protein;CAR;CAR4/6;coxsackie virus and adenovirus receptor;coxsackievirus and adenovirus receptor;coxsackievirus B-adenovirus receptor;CVB3-binding protein;HCAR;HCVADR.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells; a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding; JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
- Gene Details:
- CXADR Ig-like cell adhesion molecule
- Host:
- E. coli
- Molecular Weight:
- 27kDa
- Protein Details:
- Coxsackievirus and adenovirus receptor
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
