CHD5 Recombinant Protein
Product Sizes
10ug
£268.00
OPCD02192-10UG
50ug
£511.00
OPCD02192-50UG
200ug
£918.00
OPCD02192-200UG
About this Product
- SKU:
- OPCD02192
- Additional Names:
- ATP-dependent helicase CHD5;CHD-5;chromodomain-helicase-DNA-binding protein 5.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel; it may also positively regulate the trimethylation of histone H3 at 'Lys-27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor; it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway; which in turn; prevents cell proliferation. In spermatogenesis; it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin; a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
- Gene Details:
- chromodomain helicase DNA binding protein 5
- Host:
- E. coli
- Molecular Weight:
- 25kDa
- Protein Details:
- Chromodomain-helicase-DNA-binding protein 5
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
