CD6 Recombinant Protein
Product Sizes
10ug
£261.00
OPCD02037-10UG
50ug
£500.00
OPCD02037-50UG
200ug
£897.00
OPCD02037-200UG
About this Product
- SKU:
- OPCD02037
- Additional Names:
- CD6 antigen;T12;T-cell differentiation antigen CD6;TP120.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703; PubMed:15294938; PubMed:16352806; PubMed:16914752; PubMed:24945728; PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938; PubMed:16352806; PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938; PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777).
- Gene Details:
- CD6 molecule
- Host:
- E. coli
- Molecular Weight:
- 27kDa
- Protein Details:
- T-cell differentiation antigen CD6
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
