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Proteins and Peptides

CASP3 Recombinant Protein

Product Sizes
10ug
£279.00
OPCD01887-10UG
50ug
£539.00
OPCD01887-50UG
200ug
£977.00
OPCD01887-200UG
About this Product
SKU:
OPCD01887
Additional Names:
A830040C14Rik;AC-;AC-3;apopain;Casp;CASP-3;caspase 3; apoptosis related cysteine protease;caspase-3;CC3;CPP;CPP32;CPP-32;cysteine protease CPP32;Lice;mld;mldy;protein Yama;SCA-1;SREBP cleavage activity 1;Ya;Yama.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6; -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala; releasing the mature cytokine which is involved in a variety of inflammatory processes.
Gene Details:
caspase 3
Host:
E. coli
Molecular Weight:
20kDa
Protein Details:
Caspase-3
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins