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Proteins and Peptides

CASP1 Recombinant Protein

Product Sizes
10ug
£246.00
OPCD01869-10UG
50ug
£463.00
OPCD01869-50UG
200ug
£825.00
OPCD01869-200UG
About this Product
SKU:
OPCD01869
Additional Names:
Casp;CASP-1;caspase-1;IC;ICE;Il1;IL-1 beta-converting enzyme;IL-1B converting enzyme;Il1bc;IL-1BC;interleukin-1 beta convertase;interleukin-1 beta-converting enzyme;p45.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala; releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity). Upon inflammasome activation; during DNA virus infection but not RNA virus challenge; controls antiviral immunity through the cleavage of CGAS; rendering it inactive (PubMed:28314590).
Gene Details:
caspase 1
Host:
E. coli
Molecular Weight:
23kDa
Protein Details:
Caspase-1
Purity:
> 97%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins