CAMK2B Recombinant Protein
Product Sizes
10ug
£268.00
OPCD01841-10UG
50ug
£511.00
OPCD01841-50UG
200ug
£918.00
OPCD01841-200UG
About this Product
- SKU:
- OPCD01841
- Additional Names:
- calcium/calmodulin-dependent protein kinase type II subunit beta;CaM kinase II beta subunit;CAM2;CAMK2;CAMKB;caMK-II subunit beta;CaMKIIbeta;CaM-kinase II beta chain;MRD54;proline rich calmodulin-dependent protein kinase.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation; and is involved in dendritic spine and synapse formation; neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons; plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A; which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons; promotes arborization of the dendritic tree and in mature neurons; promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles; is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin; a ryanodine receptor-coupling factor; and phospholamban (PLN/PLB); an endogenous inhibitor of SERCA2A/ATP2A2.
- Gene Details:
- calcium/calmodulin dependent protein kinase II beta
- Host:
- E. coli
- Molecular Weight:
- 38kDa
- Protein Details:
- Calcium/calmodulin-dependent protein kinase type II subunit beta
- Purity:
- >90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
