CACNA1C Recombinant Protein
Product Sizes
10ug
£272.00
OPCD01816-10UG
50ug
£528.00
OPCD01816-50UG
200ug
£955.00
OPCD01816-200UG
About this Product
- SKU:
- OPCD01816
- Additional Names:
- brain class C;calcium channel voltage-dependent alpha1c subunit;Calcium channel; L type; alpha-1 polypeptide; isoform 1; cardiac muscle;Cav1;Cav1.2;Cchl1;Cchl1a1;D930026N18Rik;MBC;MELC-CC;Mouse brain class C;neuronal voltage-gated calcium channel alpha 1C subunit;skeletal muscle-specific calcium channel;voltage-dependent L-type calcium channel subunit alpha-1C;voltage-gated calcium channel subunit alpha Cav1.2.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes; including muscle contraction; hormone or neurotransmitter release; gene expression; cell motility; cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP); phenylalkylamines; benzothiazepines; and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. The various isoforms display marked differences in the sensitivity to DHP compounds. Binding of calmodulin or CABP1 at the same regulatory sites results in opposite effects on the channel function.
- Gene Details:
- calcium channel; voltage-dependent; L type; alpha 1C subunit
- Host:
- E. coli
- Molecular Weight:
- 25kDa
- Protein Details:
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
