AURKC Recombinant Protein
Product Sizes
10ug
£268.00
OPCD01555-10UG
50ug
£517.00
OPCD01555-50UG
200ug
£929.00
OPCD01555-200UG
About this Product
- SKU:
- OPCD01555
- Additional Names:
- AI;AIE1;AIK3;ARK-3;aurora 3;aurora B;aurora kinase C;aurora/Ipl1/Eg2 protein 1;aurora/IPL1-related kinase 3;aurora-related kinase 3;IA;IAK3;serine/threonine kinase 13 (aurora/IPL-like);serine/threonine-protein kinase 13;serine/threonine-protein kinase aurora-C;Stk1;Stk13.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC); a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB; AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1; another protein involved in cell division; at 'Ser-228'.
- Gene Details:
- aurora kinase C
- Host:
- E. coli
- Molecular Weight:
- 31kDa
- Protein Details:
- Aurora kinase C
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
