ALOX12 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD01256-10UG
50ug
£550.00
OPCD01256-50UG
200ug
£994.00
OPCD01256-200UG
About this Product
- SKU:
- OPCD01256
- Additional Names:
- 12-LOX;12S-lipoxygenase;12S-LOX;arachidonate (12S)-lipoxygenase;arachidonate (15S)-lipoxygenase;Arachidonate 12-lipoxygenase; 12S-type;arachidonate 15-lipoxygenase;15S-type;linoleate 13S-lipoxygenase;lipoxin synthase 12-LO;LOG12;platelet 12-LOX;platelet-type 12-lipoxygenase;platelet-type lipoxygenase 12;polyunsaturated fatty acid lipoxygenase ALOX12.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process; promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
- Gene Details:
- arachidonate 12-lipoxygenase; 12S type
- Host:
- E. coli
- Molecular Weight:
- 38kDa
- Protein Details:
- Arachidonate 12-lipoxygenase; 12S-type
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
